We use these shirts and none other for our "girlie fit" tees for our small etsy based business. We love how soft and comfortable these are. They definitely stand apart from a more traditional "unisex" shirt. I would NOT say they run SMALL -- they fit CLOSE or SNUG. Compare any "ladies" tee to a regular tee and you are going to notice a closer cut on the ladies tee... these are no different. They are very trendy and wash well. We get a lot of compliments on them. If you have a young lady that does not like a tight(er) fitting top, then I would NOT use these.